Research output

Publications

Lumped Parameter Bioheat Equation Formulated for System-Level Body Temperature Prediction
Heat Transfer Engineering, pp. 1–16 (2026)
Simay Akay, Canberk Yıldırım, Hakan Ertürk, Kerem Pekkan
Systolic Septal Curvature Ratio as a Cardiac MRI Marker of Right Ventricular Loading in Pediatric Congenital Heart Disease
Pediatric Cardiology (2026)
Ilker Kemal Yucel, Kevser Banu Kose, Isa Ozyılmaz, Muhammed Faruk Kazanbas, Tuba Banaz, Berk Tutuncuoglu, Yigit Can Kartal, Halise Zeynep Genc, Erkut Ozturk, Kerem Pekkan, Sercin Ozkok
Particle image velocimetry using deep learning augmented optical flow models
Measurement, 285, Article 122159 (2026)
Eda Nur Saruhan, Kağan Uçak, Melis Serdar, Reza Rasooli, A. Murat Tekalp, Kerem Pekkan
Simulating physiological blood maintenance: A dialysis-integrated in vitro flow loop for realistic hemocompatibility evaluation of devices
The International Journal of Artificial Organs, 49(7), pp. 431–442 (2026)
Tansu Gölcez, Demet Kul, Elif Uğurel, İrem Günaydın, Özlem Yalçın, Kerem Pekkan, Yahya Yıldız
Biodegradable stents and occluders in CHD: current evidence, biomechanical constraints, and translational challenges
Cardiology in the Young, 36(5), pp. 888–896 (2026)
Sercin Ozkok, Banu Kose, Ilker Kemal Yucel, Tansu Golcez, Muhammad Umair, Mohammed Eid Kaakeh, Mohammed Saloukha, Tuba Banaz, Berk Tutuncuoglu, Muhammed Faruk Kazanbas, Kerem Pekkan
Artificial valved conduits for cardiac reconstructive procedures and methods for their production
US Patent Application 19/645,039
M. Yoshida, C. D. Bernstein, O. Dur, Kerem Pekkan
Biventricular assist system
US Patent Application 18/730,345
Ibrahim Basar Aka, Kerem Pekkan, Canberk Yıldırım
Computer-generated Clinical Decision-making in the Treatment of Pulmonary Atresia with Intact Ventricular Septum
Cardiovascular Engineering and Technology, 16(2), pp. 222–237 (2025)
Canberk Yıldırım, Berk Ural, Ender Odemis, Samir Donmazov, Kerem Pekkan
Effect of impeller rotational phase on the FDA blood pump velocity fields
Artificial Organs, 48(10), pp. 1126–1137 (2024)
Kagan Ucak, Faruk Karatas, Kerem Pekkan
Review of machine learning techniques in soft tissue biomechanics and biomaterials
Cardiovascular Engineering and Technology, 15(5), pp. 522–549 (2024)
Samir Donmazov, Eda Nur Saruhan, Kerem Pekkan, Senol Piskin
Synchronous PIV measurements of a self-powered blood turbine and pump couple for right ventricle support
Scientific Reports, 14(1), Article 19962 (2024)
Kagan Ucak, Faruk Karatas, Emre Cetinkaya, Kerem Pekkan
Mechanical characterization and torsional buckling of pediatric cardiovascular materials
Biomechanics and Modeling in Mechanobiology, 23(3), pp. 845–860 (2024)
Samir Donmazov, Senol Piskin, Tansu Gölcez, Demet Kul, Ahmet Arnaz, Kerem Pekkan
Evaluation of the total hydrodynamic energy loss using 4D flow MRI in a case with Fontan failure
Heliyon, 10(6), Article e28140 (2024)
Ender Odemis, Terman Gumus, İbrahim Başar Aka, Sercin Ozkok, Kerem Pekkan
Characterization and comparative evaluation of polysulfone and polypropylene hollow fiber membranes for blood oxygenators
Journal of Applied Polymer Science, 141(12), Article e55121 (2024)
Oğuz Orhun Teber, Ayşegül Derya Altinay, Seyed Ali Naziri Mehrabani, Bihter Zeytuncu, Esra Ateş‐Genceli, Ebru Dulekgurgen, Tansu Gölcez, Yahya Yıldız, Kerem Pekkan, İsmail Koyuncu
Interstitial flow, pressure and residual stress in the aging carotid artery model in FEBio
Biomechanics and Modeling in Mechanobiology, 23(1), pp. 179–192 (2024)
Sercan Altundemir, S Samaneh Lashkarinia, Kerem Pekkan, A Kerem Uğuz
Optimizing percutaneous pulmonary valve implantation with patient-specific 3D-printed pulmonary artery models and hemodynamic assessment
Frontiers in Cardiovascular Medicine, 10, Article 1331206 (2024)
Ender Odemis, Ibrahim Basar Aka, Mhd Homam Alhaj Ali, Terman Gumus, Kerem Pekkan
Modulation of mechanosensitive genes during embryonic aortic arch development
Developmental Dynamics, 254(3), pp. 222–239 (2025)
Hummaira Banu Siddiqui, Tansu Golcez, Merve Çelik, Börteçine Sevgin, Mervenur Çoban, İlke Süder, Özen Kaya, Nesrin Özören, Kerem Pekkan
Switching the Left and the Right Hearts: A Novel Bi-ventricle Mechanical Support Strategy with Spared Native Single-Ventricle
Annals of Biomedical Engineering, 51(12), pp. 2853–2872 (2023)
Emrah Şişli, Canberk Yıldırım, İbrahim Başar Aka, Osman Nuri Tuncer, Yüksel Atay, Mustafa Özbaran, Kerem Pekkan
Synchronous PIV analysis of a self-powered blood turbine-pump couple
76th APS DFD, 2023
Kerem Pekkan, Kagan Ucak, Faruk Karatas
Surgical and transcatheter pulmonary valve replacement in patients with repaired tetralogy of Fallot: cardiac magnetic resonance imaging characteristics and morphology of right ventricular outflow tract
Pediatric Radiology, 53(9), pp. 1863–1873 (2023)
Sercin Ozkok, Hatice Ozge Ciftci, Kevser Banu Kose, Ilker Kemal Yucel, Ahmet Sasmazel, Ahmet Celebi, Kerem Pekkan
Mechanical Characterization and Torsional Buckling Effects of Pediatric Vascular Patches
Biomechanics and Modeling in Mechanobiology, 23(3), pp. 845–860 (2024)
Samir Donmazov, Senol Piskin, Ahmet Arnaz, Kerem Pekkan
Left Atrial Ligation in the Avian Embryo as a Model for Altered Hemodynamic Loading During Early Vascular Development
Journal of Visualized Experiments, Issue 196, Article e65330 (2023)
B Sevgin, MN Coban, F Karatas, K Pekkan
Artificial valved conduits for cardiac reconstructive procedures and methods for their production
US Patent US20230363896A1
Masahiro Yoshida, C. Douglas Bernstein, Onur Dur, Kerem Pekkan
Tension controlled hollow-fiber winding machine for blood oxygenator prototypes
HardwareX, 14, Article e00434 (2023)
E AliAbbasi, A Akseki, A Ullah, K Pekkan
Myocardial Biomechanics and the Consequent Differentially Expressed Genes of the Left Atrial Ligation Chick Embryonic Model of Hypoplastic Left Heart Syndrome
Annals of Biomedical Engineering, 51(5), pp. 1063–1078 (2023)
S Samaneh Lashkarinia, Wei Xuan Chan, Efthymios Motakis, Sheldon Ho, Hummaira Banu Siddiqui, Mervenur Coban, Bortecine Sevgin, Kerem Pekkan, Choon Hwai Yap
Surgical and transcatheter pulmonary valve replacement in patients with repaired tetralogy of Fallot: cardiac magnetic resonance imaging characteristics and morphology of right ventricular outflow tract
Pediatric Radiology, 53(9), pp. 1863–1873 (2023)
Sercin Ozkok, Hatice Ozge Ciftci, Kevser Banu Kose, Ilker Kemal Yucel, Ahmet Sasmazel, Ahmet Celebi, Kerem Pekkan
Cardiac magnetic resonance T2* mapping in patients with COVID-19 pneumonia is associated with serum ferritin level?
The International Journal of Cardiovascular Imaging, 39(4), pp. 821–830 (2022)
Sercin Ozkok, Hatice Ozge Ciftci, Nursen Keles, Mesut Karatas, Kemal Emrecan Parsova, Erkan Kahraman, Furkan Durak, Kerem Pekkan, Cevdet Ugur Kocogulları, Nurettin Yiyit
Embryonic aortic arch material properties obtained by optical coherence tomography-guided micropipette aspiration
Journal of Biomechanics, 146, Article 111392 (2023)
SS Lashkarinia, G Coban, HB Siddiqui, CH Yap, K Pekkan
Computational Modeling of Transmural Flow and Shear Stress on Smooth Muscle Cells in Human Carotid Artery
Bulletin of the American Physical Society
S Altundemir, K Pekkan, K Uguz
Mechanical support of pulmonary blood flow as a strategy to support the Norwood circulation-lumped parameter model study
European Journal of Cardio-Thoracic Surgery, 62(1), Article ezac262 (2022)
Syed Murfad Peer, Canberk Yildirim, Manan Desai, Karthik Ramakrishnan, Pranava Sinha, Richard Jonas, Can Yerebakan, Kerem Pekkan
A novel Fontan Y-graft for interrupted inferior vena cava and azygos continuation
Interactive CardioVascular and Thoracic Surgery, 34(6), pp. 1095–1105 (2022)
S Samaneh Lashkarinia, Murat Cicek, Banu Kose, Mohammad Rezaeimoghaddam, Emine Hekim Yılmaz, Numan Ali Aydemir, Reza Rasooli, Sercin Ozkok, Nurgul Yurtseven, Hasan Erdem, Kerem Pekkan, Ahmet Sasmazel
In vitro measurement of hepatic flow distribution in Fontan vascular conduits: Towards rapid validation techniques
Journal of Biomechanics, 137, Article 111092 (2022)
R Rasooli, B Kose, SS Lashkarinia, A Sasmazel, K Pekkan
Self-propelled venous blood pump
US Patent 11,311,713
K Pekkan
Blood Organ Culture for Testing Flow Induced Hemolysis of Extracorporeal Membrane Oxygenator Prototypes
Turkish Journal of Intensive Care
TG Köse, Y Yıldız, E Göksel, BZ Gökoğlu, K Pekkan, Ö Yalçın
Polymeric hollow fiber membrane oxygenators as artificial lungs: A review
Biochemical Engineering Journal, 180, Article 108340 (2022)
Oğuz Orhun Teber, Ayşegül Derya Altinay, Seyed Ali Naziri Mehrabani, Reyhan Sengur Tasdemir, Bihter Zeytuncu, Esra Ateş Genceli, Ebru Dulekgurgen, Kerem Pekkan, İsmail Koyuncu
Soft-Tissue Material Properties and Mechanogenetics during Cardiovascular Development
Journal of Cardiovascular Development and Disease, 9(2), p. 64 (2022)
HB Siddiqui, S Dogru, SS Lashkarinia, K Pekkan
Switching the left and the right hearts: A novel bi-ventricle mechanical support strategy with spared native single-ventricle
bioRxiv (2022) · Preprint
E Sisli, K Pekkan, C Yildirim, IB Aka, ON Tuncer, Y Atay, M Ozbaran
A novel method for hemodynamic analysis of penile erection
International Journal of Impotence Research, 34(1), pp. 55–63 (2022)
C Yildirim, H Erturk, K Pekkan, S Deniz, EC Serefoglu
Patient-specific hemodynamics of new coronary artery bypass configurations
Cardiovascular Engineering and Technology, 11(6), pp. 663–678 (2020)
Mohammad Rezaeimoghaddam, Gokce Nur Oguz, Mehmet Sanser Ates, Tijen Alkan Bozkaya, Senol Piskin, S Samaneh Lashkarinia, Erhan Tenekecioglu, Haldun Karagoz, Kerem Pekkan
Endothelial shear stress and vascular remodeling in bioresorbable scaffold and metallic stent
Journal of the American College of Cardiology, 74(13), p. B169 (2019)
Erhan Tenekecioglu, Yuki Katagiri, Kuniaki Takahashi, Mariusz Tomaniak, Dariusz Dudek, Angel Cequier, Didier Carrié, Andrés Iñiguez, Rinse Johannes van der Schaaf, Marcello Dominici, Ad J van Boven, Steffen Helqvist, Manel Sabaté, Andreas Baumbach, Jan J Piek, Joanna J Wykrzykowska, Pieter Kitslaar, Jouke Dijkstra, Johan HC Reiber, Bernard Chevalier, Dilek Ural, Kerem Pekkan, Christos V Bourantas, Frank Gijsen, Yoshinobu Onuma, Ryo Torii, Patrick W Serruys
A novel method for hemodynamic analysis of penile erection
International Journal of Impotence Research, 34(1), pp. 55–63 (2022)
Springer Nature
Spatiotemporal remodeling of embryonic aortic arch: Stress distribution, microstructure, and vascular growth in silico
Biomechanics and Modeling in Mechanobiology, 19(5), pp. 1897–1915 (2020)
SS Lashkarinia, G Çoban, E Ermek, M Çelik, K Pekkan
System for pre-operative development of patient-specific vascular patch graft prototypes for pediatric and neonatal patients
US Patent 10,729,529
K Pekkan, S Piskin
Operation scenario flow and mechanical modeling and analysis system of cardiovascular repair operations for newborn and foetus
US Patent 10,639,103
S Piskin, K Pekkan, MB Yigit
Microstructure of early embryonic aortic arch and its reversibility following mechanically altered hemodynamic load release
American Journal of Physiology-Heart and Circulatory Physiology, 318(5), pp. H1208–H1218 (2020)
Merve Celik, Selda Goktas, Cansu Karakaya, Ayse Idil Cakiroglu, Sercin Karahuseyinoglu, S Samaneh Lashkarinia, Erhan Ermek, Kerem Pekkan
Hemodynamics of neonatal double lumen cannula malposition
Perfusion, 35(4), pp. 306–315 (2020)
Muhammad Jamil, Mohammad Rezaeimoghaddam, Bilgesu Cakmak, Yahya Yildiz, Reza Rasooli, Kerem Pekkan, Ece Salihoglu
Infusion jet flow control in neonatal double lumen cannulae
Journal of Biomechanical Engineering, 142(5), Article 051002 (2020)
R Rasooli, Y Yıldız, M Jamil, K Pekkan
Artificial valved conduits for cardiac reconstructive procedures and methods for their production
US Patent 10,624,737
M Yoshida, CD Bernstein, O Dur, K Pekkan
The impact of plaque type on strut embedment/protrusion and shear stress distribution in bioresorbable scaffold
European Heart Journal - Cardiovascular Imaging, Article jez155 (2019)
Ryo Torii, Erhan Tenekecioglu, Yuki Katagiri, Ply Chichareon, Yohei Sotomi, Jouke Dijkstra, Taku Asano, Rodrigo Modolo, Kuniaki Takahashi, Hans Jonker, Robert van Geuns, Yoshinobu Onuma, Kerem Pekkan, Christos V Bourantas, Patrick W Serruys
Acknowledgement to Reviewers of Journal of Cardiovascular Development and Disease in 2019
Journal of Cardiovascular Development and Disease, 7(1), p. 7 (2020)
JCDD Editorial Office
Applications of micro-CT in cardiovascular engineering and bio-inspired design
Micro-computed Tomography (micro-CT) in Medicine and Engineering, pp. 171–181 (2020)
B Çakmak, E Ermek, M Jamil, A Horasan, K Pekkan
Transitional fetal hemodynamics and gas exchange in premature postpartum adaptation: immediate vs. delayed cord clamping
Maternal Health, Neonatology and Perinatology, 5(1), Article 5 (2019)
B Yigit, E Tutsak, C Yıldırım, D Hutchon, K Pekkan
The effect of strut protrusion on local shear stress and neointimal hyperplasia
European Heart Journal, 40(Supplement_1), Article ehz746.0573 (2019)
E Tenekecioglu, Y Katagiri, R Torii, K Pekkan, Y Onuma, PW Serruys
P5631 The impact of plaque type on strut embedment/protrusion and shear stress distribution in bioresorbable scaffold
European Heart Journal, 40(Supplement_1), Article ehz746.0575 (2019)
E Tenekecioglu, R Torii, Y Katagiri, J Dijkstra, R Modolo, K Pekkan
P5629 The effect of strut protrusion on local shear stress and neointimal hyperplasia
European Heart Journal, 40(Supplement_1), Article ehz746.0573 (2019)
E Tenekecioglu, Y Katagiri, R Torii, K Pekkan, Y Onuma, PW Serruys
TCT-172 Hemodynamic Analysis of New Version Mirage Bioresorbable Scaffold and Metallic Ultimaster Stent: A New Era Begins With Shear Stress Analysis in Stent Assessment
Journal of the American College of Cardiology, 74(13), p. B171 (2019)
E Tenekecioglu, R Torii, Y Katagiri, RJ Van Geuns, K Pekkan,
TCT-183 The Impact of Atherosclerotic Plaque Type on Strut Penetration and Local Hemodynamics in Bioresorbable Scaffolds
Journal of the American College of Cardiology, 74(13), p. B182 (2019)
E Tenekecioglu, R Torii, Y Katagiri, Y Sotomi, T Asano, J Dijkstra,
Heart valve inspired and multi‐stream aortic cannula: Novel designs for cardiopulmonary bypass improvement in neonates
Artificial Organs, 43(10), pp. E233–E248 (2019)
R Rasooli, K Pekkan
Thrust and hydrodynamic efficiency of the bundled flagella
Micromachines, 10(7), p. 449 (2019)
U Danis, R Rasooli, CY Chen, O Dur, M Sitti, K Pekkan
TCTAP A-064 The Impact of Plaque Type on Strut Embedment/Protrusion and Shear Stress Distribution in Bioresorbable Scaffold
Journal of the American College of Cardiology, 73(15), p. S32 (2019)
Erhan Tenekecioglu, Yuki Katagiri, Ryo Torii, Yoshinobu Onuma, Kerem Pekkan, Robert Van Geuns, Christos V Bourantas, Patrick W Serruys
Post-implantation shear stress assessment: an emerging tool for differentiation of bioresorbable scaffolds
The International Journal of Cardiovascular Imaging, 35(3), pp. 409–418 (2019)
Erhan Tenekecioglu, Ryo Torii, Yuki Katagiri, Ply Chichareon, Taku Asano, Yosuke Miyazaki, Kuniaki Takahashi, Rodrigo Modolo, Rasha Al-Lamee, Kadem Al-Lamee, Carlos Colet, Johan HC Reiber, Kerem Pekkan, Robert van Geuns, Christos V Bourantas, Yoshinobu Onuma, Patrick W Serruys
Effect of modified Blalock-Taussig shunt anastomosis angle and pulmonary artery diameter on pulmonary flow
The Anatolian Journal of Cardiology, 20(1), pp. 2–8 (2018)
Arnaz A, Senol P, Oguz GN, Yalcinbas Y, Pekkan K, Sarioglu T		Download
Patient-Specific Atrial Hemodynamics of a Double Lumen Neonatal Cannula in Correct Caval Position
Artificial Organs, 42(4), pp. 401–409 (2018)
Jamil M, Cakmak B, Salihoglu E, Yıldız Y, Pekkan K		Download
In vitro validation of a self-driving aortic-turbine venous-assist device for Fontan patients
The Journal of Thoracic and Cardiovascular Surgery, 156(1), pp. 292–301.e7 (2018)
Pekkan K, Aka IB, Tutsak E, Emek E, Balim H, Lazoglu I, Turkoz R		Download
Real-World Variability in the Prediction of Intracranial Aneurysm Wall Shear Stress
Cardiovascular Engineering and Technology, 9(4), pp. 544–564 (2018)
Valen-Sendstad K. et. al.		Download
Computational Pre-surgical Planning of Arterial Patch Reconstruction: Parametric Limits and In Vitro Validation
Annals of Biomedical Engineering, 46(9), pp. 1292–1308 (2018)
Lashkarinia SS, Piskin S, Bozkaya TA, Salihoglu E, Yerebakan C, Pekkan K		Download
Patient-Specific Atrial Hemodynamics of a Double Lumen Neonatal Cannula in Correct Caval Position
Artificial Organs, 42(4), pp. 401–409 (2018)
Jamil M, Rezaeimoghaddam M, Cakmak B, Yildiz Y, Pekkan K, Salihoglu E		Download
Post-implantation shear stress assessment: An emerging tool for differentiation of bioresorbable scaffolds
The International Journal of Cardiovascular Imaging, 35(3), pp. 409–418 (2019)
Tenekecioglu E, Torii R, Katagiri T, et. al.		Download
Asymmetry in Mechanosensitive Gene Expression during Aortic Arch Morphogenesis
Scientific Reports, 8(1), Article 16948 (2018)
Karakaya C, Goktas S, Celik M, Keller B, Pekkan K		Download
Computational pre-surgical planning of arterial patch reconstruction - parametric limits and in vitro validation
Annals of Biomedical Engineering, 46(9), pp. 1292–1308 (2018)
Lashkarinia S, Piskin S, Tijen A B, Salihoglu E, Yerebakan C, Pekkan K		Download
Aortic Outflow Cannula Tip Design and Orientation impacts Cerebral Perfusion During Pediatric Cardiopulmonary Bypass Procedures
Annals of Biomedical Engineering, 41(12), pp. 2588–2602 (2013)
Menon et.al.		Download
High-speed three-dimensional characterization of fluid flows induced by micro-objects in deep microchannels
BioChip Journal, 7(2), pp. 95–103 (2013)
Chen and Pekkan		Download
Guest Editorial: Special Issue on Fetal Hemodynamics, Developmental Fetal Cardiovascular Biomechanics in the 21st Century
Cardiovascular Engineering and Technology, 4(3), pp. 231–233 (2013)
Pekkan and Keller		Download
Critical transitions in early embryonic aortic arch patterning and hemodynamics
PLoS ONE, 8(3), p. e60271 (2013)
Kowalski, Dur, et. al.		Download
Patient-specific hemodynamic performance of Fontan conversion templates: Lateral tunnel vs. intra-atrial with fenestration
Pediatric Cardiology, 34(6), pp. 1447–1454 (2013)
Hong, Dur, et. al.		Download
Time-resolved OCT-μPIV: A new microscopic PIV technique for noninvasive depth-resolved pulsatile flow profile acquisition
Experiments in Fluids, 54(1), Article 1426 (2013)
Chen, Menon, et. al.		Download
Computer modeling for the prediction of thoracic aortic stent graft collapse
Journal of Vascular Surgery, 54(3), p. 925 (2011)
Pasta, Chod, et. al.		Download
Characterization of neonatal aortic cannula jet flow regimes for improved cardiopulmonary bypass
Journal of Biomechanics, 46(2), pp. 362–372 (2013)
Menon, Teslovich, et. al.		Download
Pre-Surgical Evaluation of Fontan Connection Options for Patients with Apicocaval Juxtaposition, using Computational Fluid Dynamics
Artificial Organs, 37(1), pp. E1–E8 (2013)
Menon, Yoshida, Pekkan		Download
Variability of CFD Solutions for Pressure and Flow in a Giant Aneurysm: The SBC2012 CFD Challenge
Journal of Biomechanical Engineering, 135(2), Article 021016 (2013)
Steinman, et. al.		Download
Novel fenestration designs for controlled venous flow shunting in failing Fontans with systemic
Artificial Organs, 37(1), pp. 66–75 (2013)
Priti, Menon, et. al.		Download
Total cavopulmonary connection for patients with apicocaval juxtaposition: Consideration about the optimal route of conduit using preoperative angiography and flow simulation
European Journal of Cardio-Thoracic Surgery, 44(1), pp. e46–e52 (2013)
Yoshida, et.al.		Download